Frankfurt: +49 69 664 29 124
We speak: DE, EN, RU.

Name1 procedurePrice per procedure when purchasing packagesBook
3
Biostimulation polynucleotides for face, neck, decollete, hands
310€
249€ 310€
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Under-eye area (dark circles)
389€
310€ 389€
Book now
Pay in installments with MediPay
Plan your treatment now and spread the cost with convenient monthly installments.
Pay in installments with MediPay
For those who prefer more flexible payment options, we offer the possibility to pay in installments through our partner MediPay.
After choosing your treatment, the center will send you a MediPay application link via email or SMS. Once you complete the online form, a quick credit check is performed. If approved, the contract can be confirmed digitally.
MediPay pays the full amount directly to the center, and you can spread the cost into convenient monthly installments according to the plan that suits you best.

Polynucleotides Frankfurt – modern biostimulation with Nucleofill®

At ERA ESTHETIC Frankfurt, we work with modern polynucleotide technologies such as Nucleofill® – one of Europe’s most innovative regenerative anti-aging treatments. The goal: to improve skin quality, not to change the face.

Polynucleotides are among the most advanced biostimulators in aesthetics. They support cell regeneration, collagen production, hydration, tissue stability, and natural skin renewal. As a result, the skin structure is visibly improved – without an artificial effect.

Book your personal consultation now.

How do polynucleotides work – polynucleotide treatment in Frankfurt

The treatment activates:

  • Fibroblasts
  • Collagen production
  • Hydration
  • Cell regeneration
  • Antioxidant protection

This stabilizes and rebuilds the skin from within.

For patients, this means:

  • fresher-looking skin
  • more radiance
  • a less tired appearance
  • smoother skin texture
  • greater firmness
  • a naturally younger appearance

The results develop gradually and naturally. This is exactly why polynucleotides provide such a high-quality effect. Not artificial. Not exaggerated. Regenerative.

Polynucleotides Frankfurt – the difference between polynucleotides, fillers, and hyaluronic acid

Many patients ask:

“Is Nucleofill a filler?”

No. Traditional fillers create volume. Polynucleotides improve skin quality.

This means:

  • no artificial contours
  • no overfilled facial features
  • no changes to the shape of the face

Instead:

  • genuine skin regeneration
  • improved skin texture
  • greater firmness
  • a fresher appearance

The treatment is therefore ideal for patients who want to maintain a natural appearance.

Who is suitable for polynucleotide treatment in Frankfurt?

The treatment is particularly suitable for dark circles, under-eye bags, fine lines, tired-looking skin, dry skin, early signs of skin aging, and sensitive skin.

The treatment can also visibly improve skin quality in cases of a dull complexion and reduced firmness.

Book your personal consultation now.

Polynucleotides Frankfurt – popular treatment areas

Polynucleotides can be used on the:

  • Eye area
  • Face
  • Neck
  • Décolletage
  • Hands
  • Hairline / scalp

Polynucleotide treatment for the eyes in Frankfurt is particularly popular for naturally improving the delicate eye area.

Polynucleotide treatment procedure in Frankfurt

First, we analyze the skin quality, moisture levels, elasticity, eye area, and individual skin needs.

The polynucleotides are then precisely injected into the desired areas. The treatment usually takes approximately 20–30 minutes.

Benefits:

  • minimally invasive
  • no downtime
  • immediate return to everyday activities
  • natural-looking effect

Polynucleotides before and after: what results are possible?

Many clients report fresher-looking skin, a less tired eye area, increased radiance, and a softer skin texture after only a short time.

As the treatment progresses, the following improvements are also frequently observed:

  • reduced dark circles
  • fewer fine lines
  • greater firmness
  • smoother skin
  • improved skin quality

The goal is not an artificial change. The goal is skin that looks healthy, fresh, and refined.

How long do the results last?

Skin quality improves gradually and over the long term. Maintenance treatments help preserve stable results.

Modern regenerative technologies at ERA ESTHETIC Frankfurt

At ERA ESTHETIC Frankfurt, we combine modern regenerative systems from Promoitalia:

  • Polynucleotides
  • Synthetic exosomes
  • Biomimetic peptides
  • Plant stem cells

This allows active ingredients to be absorbed in an even more targeted manner.

Benefits:

  • more intensive regeneration
  • improved hydration
  • more stable results
  • more natural-looking skin quality

We also use modern exosome technologies to support cell communication and skin renewal.

Why choose ERA ESTHETIC Frankfurt?

At ERA ESTHETIC Frankfurt, we combine advanced regenerative technologies, high-quality active ingredients, natural anti-aging concepts, individual skin analysis, and aesthetic expertise.

Our focus: visible skin improvement without an artificial effect. Natural. Elegant. Modern.

Appointment for polynucleotide treatment in Frankfurt

Natural skin rejuvenation does not begin with change, but with genuine regeneration.

Polynucleotide treatment in Frankfurt can help the skin look visibly fresher, smoother, and more rested.

Book your personal skin analysis and consultation at ERA ESTHETIC Frankfurt now.

FAQ

What are polynucleotides?

Polynucleotides are naturally occurring molecules with regenerative properties. They support cell regeneration, collagen production, and the skin’s natural renewal process. In aesthetic medicine, they are used to visibly improve skin quality without artificially changing the appearance of the face. This is why polynucleotides are considered a modern approach to regenerative skin rejuvenation.

What is the difference between polynucleotides and hyaluronic acid?

Hyaluronic acid fillers are primarily used to restore volume and contour specific areas of the face. Polynucleotides, on the other hand, focus on improving skin quality by supporting the skin’s natural regeneration and enhancing its overall structure.

When will I see results after a polynucleotide treatment in Frankfurt?

Many patients notice the first improvements after their initial treatment sessions. The skin often appears more hydrated, fresher, and less tired. However, the full regenerative effect develops gradually over several weeks.

Is polynucleotide treatment painful?

The treatment is generally well tolerated. Mild redness or slight swelling may occur immediately after the procedure, but these effects usually subside within a short time.

How many treatment sessions will I need?

For optimal results, a series of three to four treatment sessions is often recommended. Treatments are typically scheduled about two weeks apart. Depending on your skin condition and treatment goals, the number of sessions can be adjusted individually. Maintenance treatments help preserve the results over the long term.

Can polynucleotides be combined with other treatments?

Yes. Polynucleotides are often combined with exosomes, laser treatments, skin boosters, and other regenerative therapies. This allows multiple aspects of skin aging to be addressed simultaneously.

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Frankfurt am Main: +49 69 664 29 124
Era Esthetic GmbH
Center for Aesthetics and Laser Medicine
Gerbermuehlstrasse 9
60594 Frankfurt
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